S.D. Ahmedova
Azerbaijan Medical University
Zeolites are natural aluminum silicates of volcanic origin.
Recent researches showed that zeolite supresses the biological activity of many pathogenic microorganisms and adsorbs them, accelerating the process of recovery from infec tious diseases. Aim of the research is to study the clinical effectiveness of 20% ointment and it's versions in the therapy of patients with different dermatoses.
Mateials and methods of the research. In the process of preliminary expeimental researches οn laboratory animals (horses) was revealed the effectiveness of 20% zeolitic oint ment based οn vaseline. While the following researches we have developed the following structures of zeolitic ointment:
- the zeolitic ointment riched in zinc (zeolite - 17%, zeolite, riched in metal zinc (2p) - 3%). Zinc participates in immunogenesis, different metabolic processes of the organism;
- the zeolitic ointment riched in copper (zeolit - 17% zeolite riched in metal of copper (Si) - 3%). Copper takes im portant part in antioxidant protection of the organism, because copper together with zinc enters the structure of antioxidant ferment - superoxide dismutase and antioxidant protein of blood plasma - cerruloplazmina which is the carrier of this metal. Copper possesses antiinflammatory and antiseptic characteristics.
- the zeolitic ointment riched in zinc and copper (zeolite - 17%, zeolite riched in metal of zinc) - 1,5% zeolite riched in metal of copper (Si) - 1,5% - "mixed ointment".
Also there was developed a cosmetic clearing mask for the care of skin, including the foundation (60-75%) - fine dis persed mineral sorbates from zeolite contaimimg tufa from Aydag and biologically active substances (25-40%) - the crushed medicinal vegetational raw mateials, containing in identical proportions died flowers of camomile, grass of beg gar-ticks, grass of field horsetail, leaves of nettle, grass of origan, petals of violet, thyme, root of bare licoice.
82 patients with various dermatoses at the age from 8 months till 76 years old, who have been casually selected dur ing RDVD and volunteers who agreed to have treatment with 20 % zeolitic ointment and its vaious vaiants, participated in clinical researches. Among patients at 28 ones (34,1 %) the psoiasis was diagnosed, at 26 ones (31,7 %) - puigo, at 20 (24,4 %) - atopic dermatitis, at 8 ones (9,8 %) - acrodermatitis enteropathica.
Analysis of the effectiveness of using zeolite ointment while topical therapy showed rather quicker approach of clinical effect while using mixt ointments - variant of zeolite oint ment together with Ζn and Ci. Analysis of the katamnestic data revealed the lack of syndrome of cancelling and more firm re mission for 4-9 monthes in the patients diseased of dermatitis, pruigo and psoiasis.
So zeolitic ointment is a preparation of choice at heavy skin pathologies as a exfoliating, regenerating, antipruitic, sedative, resrtoing the trophism topic means increasing the effectiveness of the cure of skin diseases. Dimensioned use of the zeolitic ointment in dermatology needs further biochemical and clinical-immunological researches at the level of cellular and humoral immunity.
